Pure Shift - Setting Up PSYCHE Experiment

This course will outline what pure shift experiments are, how to set up acquisition and how they are processed.  We will focus on the PSYCHE experiments and spend a significant amount of time at the spectrometer.  We will review common problems with pure shift experiments, and finish up with incorporating pure shift into 2D experiments.

Speaker

Dr. Amy Freund
Senior Applications Scientist II
Bruker BioSpin

Dr. Amy Freund is a Senior Applications Scientist II at Bruker BioSpin. Her work focuses on the utilization of high-throughput NMR in the fields of metabolomics, screening and drug discovery. Areas of expertise include quantitative NMR, decoupling techniques, cryoprobe technology, small volume NMR, and semi-solid HR-MAS NMR. She is valued for her rare mix of training, communication, and problem-solving skills. Complimenting her work training and assisting customers, Dr. Freund is product manager for AutoCalibrate, a new software tool for instrument performance monitoring and evaluation. For this project, she has taken insight gathered from her interactions with customers; conversations, troubleshooting and training to spot bottlenecks in workflows and develop a tool to streamline/automate instrument maintenance.

Dr. Freund first became interested in NMR 20 years ago during her graduate work at the University of Vermont. There she managed the NMR facility and assisted faculty and students in many different types of NMR studies. In her own graduate research, she used 19F and 31P NMR to study reaction pathways of fluorinated phosphazene monomers and polymers. She also advised researchers in their studies of organic chemistry reaction kinetics and catalytic pathways in porous materials using HR-MAS and solid-state NMR.

While previously the application team leader for Bruker’s west coast office, researchers seeking her expertise can now find her at Bruker’s US headquarters in Billerica, Massachusetts.